Congratulations to Daniel (lead), Jiaul, and Kye, who are all co-authors on a great new review in this special issue. With Kris Thurecht and I, the team performed a systematic review of the nanoparticle-based therapeutics that have been approved by the FDA, along with those in clinical trials. This is a quickly moving field, and there will be more drugs approved in this class very soon. Other studies in this special issue include work from Prof Craig Hawker (UCSB), Prof Heather Clark (Northeastern), Prof Doo Sung Lee (Sunkyunkwan), and many more.